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KMID : 0359319880280020391
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Korean Journal of Veterinary Research
1988 Volume.28 No. 2 p.391 ~ p.396
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Studies on the internal decontamination of radioiodine
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김태환/Kim, Tae Hwan
윤택구/정현우/정인용/진수일/Yun, Taik Koo/Chung, Hyun Woo/Chung, In Yong/Chin, Soo Yil
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Abstract
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Appreciable radiation exposures certainly occur in the workers who handle radioiodine in biochemical research, nuclear medicine diagnostics with the development of nuclear industries. But in the case of occurring the nuclear accidents, the early medical treatment of radiation injury should be necessary but little was reported in korea till now.
Accordingly, to achieve of the basic data for protective roles and mcedical treatment of radiation injury, the present studies were carried out to evaluate the decontamination of radioiodine by the administration of the antithyroid drugs.
The results observed are summarized as follows:
1. The administration of sodium iodide and potassium iodide results in rapid excretion of radioiodine and reduction of the whole body retention than the saline-only group.
2. Reguarding to thyroid protective effects, sodium iodide, potassium iodide and saline were effected significant in order.
3. In the control(saline) group, if administered with enough fluids, the whole body retention of radioiodine is reduced temporary shifts. But as far as radioprotective effects is concerned, saline was not more in the protective effects than the other groups.
In conclusion, in case of nuclear accidents, if being administered sodium iodide and saline as quickly as possible, the radioprotective effects against the radiation hazard might be markedly increased in the internal contamination of radioiodine.
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